Empowering Research

Innovative approaches to better understand the neural control of food intake, reward and motivation

I am passionate about understanding reward and motivation, and how they influence harmful food and drug intake. The possibility of contributing knowledge that could reduce suffering and improve well-being drives my excitement in the lab, even when data surprises me. While I have always loved the discovery process in my own lab, being part of a department’s collective achievements is even more fulfilling. As the new department head, I am thrilled to support the innovative work of talented research groups.

^{Dr. Shane Hentges is a brilliant scientist with a zest for life! When she’s not diving into research, she’s out having fun—whether it’s tackling snowy trails or climbing hills. Her adventurous spirit and friendly nature make her a joy to be around and an inspiration to all.}

Our lab is equipped with state-of-the-art technology to advance our research in neuroscience and molecular biology mice

Whole-cell electrophysiology (patch clamp)

We use this approach to assess how synaptic communication changes in hedonic and homeostatic circuits with feeding state and opioid exposure. We hope to identify ways to undo the underlying synaptic changes that encourage counterproductive food or drug intake.

Food, drugs, and behavior

We take our work from the synaptic to whole – animal levels to better understand how synaptic and behavioral changes effect each other al changes effect each other.

Opto and chemogenetic

We use a variety of approaches to visualize proteins, cells, and transcripts under various conditions.

Labeling and imaging

We use a variety of approaches to visualize proteins, cells, and transcripts under various conditions.

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